Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

Sang-Won Min, Seo-Hyun Cho, Yungui Zhou, Sebastian Schroeder, Vahram Haroutunian, William W. Seeley, Eric J. Huang, Yong Shen, Eliezer Masliah, Chandrani Mukherjee, David Meyers, Philip A. Cole, Melanie Ott, and Li Gan, Gladstone Institute of Neurological Disease, Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA, Department of Neurology, Department of Medicine, Department of Pathology, Biomedical Science and Neuroscience Graduate Program, University of California, San Francisco, CA 94143, USA, Department of Neuroscience, University of California at San Diego, La Jolla, CA 92093, USA, Department of Pharmacology and Molecular Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA, Haldeman Laboratory of Molecular and Cellular Neurobiology, Sun Health Research Institute, Sun City, AZ 85351, USA, Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY 10468, USA.Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy. Neuron 67, 953-966, September 23, 2010