Neurobiology of Learning And Memory
Research in our lab is focused on understanding how memories of past events influence the acquisition of new memory and experiences. Using mice as a model system, we follow the neuronal correlates of memory. We follow the changes accompanying acquisition, formation and retrieval of memory through in-vivo two-photon imaging. Longitudinal imaging of the same mice over the entire process of memory consolidation provides us a unique ability to watch, follow and study these processes as they happen. We combine this ability with small animal behaviour and molecular genetics to investigate
- How the internal representation of remote events (events that happened a long time ago) that are similar in nature but distinct in content are encoded.
- When such events are encoded in two (NMDAR dependent and NMDAR independent) molecularly independent pathways, how do their corresponding internal representations change at cellular and synaptic scale?
- How multiple memories interact with each other and influence future behaviour.
- What happens to temporal information in such representations of old memories.
PI : Dr.Balaji Jayaprakash (Webpage)