Research Setup

Our lab studies brain signals in two species (humans and non-human primates) and at four “levels” of recordings: spikes, local field potential (LFP), electrocorticogram (ECoG) and electroencephalogram (EEG), as shown below.

Different recording scales in humans and non-human primates

  1. Microelectrode recordings from monkeys: This allows us to record activity of single neurons using microelectrode arrays. We also get a second “level” called local field potential (LFP), which represents the local activity of a few thousand neurons, by low-pass filtering the signal.
  2. EEG from humans: Complex behaviours such as attention are studied at a coarse “network” level using EEG, in which electrodes are placed on the scalp.
  3. EEG from monkeys: We have modified our recording system that is used for microelectrode recordings to simultaneously record EEG from monkeys as well.
  4. Electrocorticogram (ECoG) from monkeys: ECoG is obtained from macro-electrodes placed directly on the brain, and is typically recorded from humans undergoing epilepsy treatment. We have collaborated with companies that make microelectrodes (Blackrock Microsystems) and ECoG arrays (Ad-Tech Medical Instrumentation) to design a hybrid electrode grid that includes both. We are therefore able to simultaneously record from four scales in monkeys (spikes, LFP, ECoG and EEG).

Summary of Projects

Project Details

Aging and Mental Disorders

We collected EEG data from a large cohort (350 recordings from 279 subjects) of elderly subjects (>50 years) while they...
Read More

Brain Stimulation

The brain can be stimulated in various ways. The first involves sensory stimulation. For example, by presenting flickering visual stimuli...
Read More

Decoding and Computation

The goal is to better understand the properties of brain signals using various signal-processing techniques for decoding and brain-machine interfacing...
Read More

Gamma oscillations

Although we record and analyze different types of brain oscillations, our focus is on "gamma" oscillations (30-80 Hz). Our grand...
Read More

Meditation and Attention

Meditation: Project Dhyaan Project Dhyaan: The goal of this project is to study the effect of various meditative practices on...
Read More