{"id":171,"date":"2015-11-24T06:31:51","date_gmt":"2015-11-24T06:31:51","guid":{"rendered":"http:\/\/localhost\/iisc-ghosh\/?page_id=171"},"modified":"2023-08-08T06:11:03","modified_gmt":"2023-08-08T06:11:03","slug":"research","status":"publish","type":"page","link":"https:\/\/cns.iisc.ac.in\/sray\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n

Research Setup<\/h2>\n\n\n\n

Our lab studies brain signals in two species (humans and non-human primates) and at four \u201clevels\u201d of recordings: spikes, local field potential (LFP), electrocorticogram (ECoG) and electroencephalogram (EEG), as shown below. <\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/a><\/figure><\/div>\n\n\n\n

Different recording scales in humans and non-human primates<\/p>\n\n\n\n

  1. Microelectrode recordings from monkeys<\/em>: This allows us to record activity of single neurons using microelectrode arrays. We also get a second \u201clevel\u201d called local field potential (LFP), which represents the local activity of a few thousand neurons, by low-pass filtering the signal.<\/li>
  2. EEG from humans:<\/em> Complex behaviours such as attention are studied at a coarse \u201cnetwork\u201d level using EEG, in which electrodes are placed on the scalp.<\/li>
  3. EEG from monkeys:<\/em> We have modified our recording system that is used for microelectrode recordings to simultaneously record EEG from monkeys as well.<\/li>
  4. Electrocorticogram (ECoG) from monkeys:<\/em> ECoG is obtained from macro-electrodes placed directly on the brain, and is typically recorded from humans undergoing epilepsy treatment. We have collaborated with companies that make microelectrodes (Blackrock Microsystems) and ECoG arrays (Ad-Tech Medical Instrumentation) to design a hybrid electrode grid that includes both. We are therefore able to simultaneously record from four scales in monkeys (spikes, LFP, ECoG and EEG).<\/li><\/ol>\n\n\n\n
    \n\n\n\n

    <\/p>\n\n\n\n

    Summary of Projects<\/h2>\n\n\n\n
    \"\"<\/a><\/figure><\/div>\n\n\n\n
    \n\n\n\n

    Project Details<\/h2>\n\n\n\r\n\t
    \r\n\t\t
    \r\n\t\t\t
    \r\n\t
    \r\n\t<\/a>\r\n\t\t
    \r\n\t\t\r\n\t\t\t

    \r\n\t\t\t\tAging and Mental Disorders<\/a>\r\n\t\t\t<\/h2>\r\n\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>\r\n\t\t\t
    \r\n\t\t\t
    We collected EEG data from a large cohort (350 recordings from 279 subjects) of elderly subjects (>50 years) while they...<\/div>\r\n\t\t\t\t\t\t\tRead More<\/a>\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>
    \r\n\t
    \r\n\t<\/a>\r\n\t\t
    \r\n\t\t\r\n\t\t\t

    \r\n\t\t\t\tBrain Stimulation<\/a>\r\n\t\t\t<\/h2>\r\n\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>\r\n\t\t\t
    \r\n\t\t\t
    The brain can be stimulated in various ways. The first involves sensory stimulation. For example, by presenting flickering visual stimuli...<\/div>\r\n\t\t\t\t\t\t\tRead More<\/a>\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>
    \r\n\t
    \r\n\t<\/a>\r\n\t\t
    \r\n\t\t\r\n\t\t\t

    \r\n\t\t\t\tDecoding and Computation<\/a>\r\n\t\t\t<\/h2>\r\n\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>\r\n\t\t\t
    \r\n\t\t\t
    The goal is to better understand the properties of brain signals using various signal-processing techniques for decoding and brain-machine interfacing...<\/div>\r\n\t\t\t\t\t\t\tRead More<\/a>\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>
    \r\n\t
    \r\n\t<\/a>\r\n\t\t
    \r\n\t\t\r\n\t\t\t

    \r\n\t\t\t\tGamma oscillations<\/a>\r\n\t\t\t<\/h2>\r\n\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>\r\n\t\t\t
    \r\n\t\t\t
    Although we record and analyze different types of brain oscillations, our focus is on \"gamma\" oscillations (30-80 Hz). Our grand...<\/div>\r\n\t\t\t\t\t\t\tRead More<\/a>\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>
    \r\n\t
    \r\n\t<\/a>\r\n\t\t
    \r\n\t\t\r\n\t\t\t

    \r\n\t\t\t\tMeditation and Attention<\/a>\r\n\t\t\t<\/h2>\r\n\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>\r\n\t\t\t
    \r\n\t\t\t
    Meditation: Project Dhyaan Project Dhyaan: The goal of this project is to study the effect of various meditative practices on...<\/div>\r\n\t\t\t\t\t\t\tRead More<\/a>\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>\t\t<\/div>\r\n\t<\/div>\r\n\r\n\t\n\n\n\n
    \n\n\n\n

    <\/p>\n","protected":false},"excerpt":{"rendered":"

    Research Setup Our lab studies brain signals in two species (humans and non-human primates) and at four \u201clevels\u201d of recordings: spikes, local field potential (LFP), electrocorticogram (ECoG) and electroencephalogram (EEG), as shown below. Different recording…<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"kt_blocks_editor_width":""},"_links":{"self":[{"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/pages\/171"}],"collection":[{"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/comments?post=171"}],"version-history":[{"count":16,"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/pages\/171\/revisions"}],"predecessor-version":[{"id":2282,"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/pages\/171\/revisions\/2282"}],"wp:attachment":[{"href":"https:\/\/cns.iisc.ac.in\/sray\/wp-json\/wp\/v2\/media?parent=171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}